eprintid: 2295
rev_number: 1
eprint_status: archive
userid: 1
dir: disk0/00/00/22/95
datestamp: 2020-04-23 05:37:42
lastmod: 2020-04-23 05:37:42
status_changed: 2020-04-23 05:37:42
type: thesis
metadata_visibility: show
creators_name: Heupink, L. F.
title: Doomed from Birth? The associations of birthweight to obesity development in later life by looking for the importance of inherited and environmental factors among German twins
ispublished: pub
full_text_status: public
abstract: Globally obesity affects over 650 million individuals. The mechanism underlying obesity is complex and no consensus on its workings prevails. Birthweight, genetic and environmental factors all have been theorized to influence obesity development. The aim of this study is to tests whether an association between birthweight and obesity in later life exists, after which the importance of genetics and social environment are determined. Data from the TwinLife project is used. The dependent variable is BMI, transformed to a z-score, with the main predictor birthweight. Further, in the regression sex, mothers’ age at birth and mothers’ education are controlled. Birthweight is positively associated with BMI when treating twins as individuals. Stratification shows when twins birthweight >2500 grams the association is significant. Within twin pair X-values are mostly insignificant. In dizygotic twins the X-value is significant, concluding that genetics and in-utero environments play a role in the association of birthweight and BMI.
date: 2018
date_type: published
thesis_type: pre_master
degree_programme: POPST
tutors_name: Vogt, T. C.
keywords_local: Nature-Nurture
keywords_local: OLS
keywords_local: Obesity
keywords_local: Twins
keywords_local: Birthweight
language_iso: en
titleorder: Doomed from Birth? The associations of birthweight to obesity development in later life by looking for the importance of inherited and environmental factors among German twins
dbi: 5bb5e031f11f4
imported_item: yes
date_of_import: 2020-04-22
imported_from: http://scripties.frw.eldoc.ub.rug.nl/root/premasters/PopulationStudies/2018/lfheupink/
import_source_file: theses-frw-20200422132455-5bb5e031f11f4.xml
date_issued: 2018-01-01
citation:   Heupink, L. F.  (2018) Doomed from Birth? The associations of birthweight to obesity development in later life by looking for the importance of inherited and environmental factors among German twins.  Pre-master thesis.   
document_url: https://frw.studenttheses.ub.rug.nl/2295/1/Master_Thesis_LF_Heupink_S2759_1.pdf