%L theses_frw2321
%A E. Witteveen
%T The association between physical environmental conditions and different groups of congenital anomalies in the northern Netherlands
%D 2020
%X The purpose of this study is to use an exploratory quantitative study design with GIS elements to investigate whether there is an association between physical environmental conditions and different groups of congenital anomalies in the northern Netherlands. Data of EUROCAT NNL is used as data source for congenital anomalies. The population consists of babies and foetuses born with non-chromosomal and non-monogenic congenital anomalies in the northern Netherlands. Different groups classified according to the organ system are included. Due to the absence of non-malformed children in the EUROCAT NNL database, congenital anomaly groups are compared with a chromosomal and monogenic congenital anomaly group. Multinomial logistic regressions are performed. Significant positive associations are found between higher percentages agricultural land and limb anomalies, intermediate concentrations nitrogen oxides and anomalies of the digestive system, higher concentrations nitrogen oxides and eye and limb anomalies, and between a high liveability situation and genital and limb anomalies.